Virtual reality has been applied to education widely since technology developed quickly. In order to apply the “Virtual Reality Vocational Skills Training System” to vocational high school students with intellectual disabilities, this study simplify the operation of the original system and develop an easy-to-use version to meet the learning needs of students with intellectual disabilities. Therefore, the purpose of this study is to test the usability of the easy-to-use version through the questionnaire, and to compare the operating efficiency between the easy-to-use version and the original one. Eight students with intellectual disabilities participated in the study. The results indicated that most students expressed that the easy-to-use version had good usability, and reduced the operation time and the number of wrong actions, as well as enhanced the accuracy. Overall, this designed “Virtual Reality Vocational Skills Training System” can be applied to the training of vocational skills for students with intellectual disabilities.