Universal behavior for characteristic curve of immunomagnetic reduction assay with aid of biofunctionalized magnetic nanoparticles

Chin Yih Hong*, Shieh Yueh Yang, Herng Er Horng, Jen Jie Chieh, Hong Chang Yang

*此作品的通信作者

    研究成果: 書貢獻/報告類型會議論文篇章

    摘要

    By biofunctionalizing magnetic nanoparticles with bioprobes, magnetic nanoparticles are able to specifically label bio-molecules. With the association between magnetic nanoparticles and bio-molecules, the mixed-frequency AC magnetic susceptibility generated with the physical rotation of individual magnetic nanoparticles under external AC magnetic fields is reduced. This detection technology is so-called immunomagnetic reduction (IMR) assay. In the experiment, several kinds of proteins and small-molecule chemicals were detected via IMR. The characteristic curves, i.e. the reduction versus the concentration of protein/chemical, for these proteins or chemicals can be scaled to one universal curve.

    原文英語
    主出版物標題ASME 2009 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, IDETC/CIE2009
    頁面397-400
    頁數4
    DOIs
    出版狀態已發佈 - 2009 十二月 1
    事件ASME 2009 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, IDETC/CIE2009 - San Diego, CA, 美国
    持續時間: 2009 八月 302009 九月 2

    出版系列

    名字Proceedings of the ASME Design Engineering Technical Conference
    6

    其他

    其他ASME 2009 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, IDETC/CIE2009
    國家/地區美国
    城市San Diego, CA
    期間2009/08/302009/09/02

    ASJC Scopus subject areas

    • 建模與模擬
    • 機械工業
    • 電腦科學應用
    • 電腦繪圖與電腦輔助設計

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