Tyrosinase/Chitosan/Reduced graphene oxide modified screen-printed carbon electrode for sensitive and interference-free detection of dopamine

Cheng You Liu, Yi Chieh Chou, Jui Hsuan Tsai, Tzu Ming Huang, Jian Zhang Chen, Yi Chun Yeh

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

摘要

Tyrosinase, chitosan, and reduced graphene oxide (rGO) are sequentially used to modify a screen-printed carbon electrode (SPCE) for the detection of dopamine (DA), without interference from uric acid (UA) or ascorbic acid (AA). The use of tyrosinase significantly improves the detection's specificity. Cyclic voltammetry (CV) measurements demonstrate the high sensitivity and selectivity of the proposed electrochemical sensors, with detection limits of 22 nM and broad linear ranges of 0.4-8 μM and 40-500 μM. The fabricated tyrosinase/chitosan/rGO/SPCE electrodes achieve satisfactory results when applied to human urine samples, thereby demonstrating their feasibility for analyzing DA in physiological samples.

原文英語
文章編號622
期刊Applied Sciences (Switzerland)
9
發行號4
DOIs
出版狀態已發佈 - 2019 二月 13

ASJC Scopus subject areas

  • Materials Science(all)
  • Instrumentation
  • Engineering(all)
  • Process Chemistry and Technology
  • Computer Science Applications
  • Fluid Flow and Transfer Processes

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