This study aimed to evaluate the efficacy of hydrodistention (HD) and bladder training for interstitial cystitis (IC). From 1997 to 2006, 361 consecutive IC patients were treated by HD, followed by bladder training. Each patient was followed up using a diary for 8 weeks after HD weekly and monthly thereafter. The efficacy of the treatment was evaluated using the average of the voided volumes and the voiding frequency. The mean ± standard deviation of the pre-HD daytime voided volumes and voiding frequency were 110.0 ± 47.0 ml and 14.7 ± 11.0, respectively. Furthermore, the nocturnal values were 173.1 ± 91.8 ml and 2.8 ± 1.7, respectively. After 72 weeks post-HD, the 185 patients who completed the follow-up had volumes/frequency of daytime, 306.5 ± 80 ml and 6.9 ± 2.1, respectively, and nocturnal, 325.8 ± 122.4 ml and 1.3 ± 0.6, respectively. The implementation of HD and bladder training is crucially important for long-term remission among IC patients.
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