Transcriptomic Changes in Hot Spring Frog Tadpoles (Buergeria otai) in Response to Heat Stress

Shohei Komaki, Masatoshi Matsunami, Jhan Wei Lin, Ko Huan Lee, Yen Po Lin, Yu Lee, Si Min Lin, Takeshi Igawa*

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

摘要

Buergeria frog tadpoles exhibit high thermal tolerance and are occasionally found in water pools that temporarily exceed 40°C. With the aim of understanding how they can cope with the severe heat stress, we performed RNA-seq of three heat-treated (38°C) and three control (25°C) tadpoles and compared their transcriptomic profiles. We identified 382 differentially expressed transcripts. A protein-protein interaction (PPI) network analysis of these transcripts further identified hub proteins involved in protein degradation, stress granule assembly, and global suppression of DNA transcription and mRNA translation. Along with the avoidance behavior against high water temperature, these endurance mechanisms potentially support tadpoles to survive in high temperatures for short periods of time. Similar mechanisms may exist in many other amphibian species whose habitats are prone to high temperatures.

原文英語
文章編號706887
期刊Frontiers in Ecology and Evolution
9
DOIs
出版狀態已發佈 - 2021 10月 13

ASJC Scopus subject areas

  • 生態學、進化論、行為學與系統學
  • 生態學

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