Three-component Synthesis of Functionalized N-Protected Tetrasubstituted Pyrroles by an Addition-Elimination-Aromatization Process

Dhananjay R. Magar, Yi Jiun Ke, Kwunmin Chen

研究成果: 雜誌貢獻期刊論文同行評審

34 引文 斯高帕斯(Scopus)

摘要

A three-component, one-pot, synthesis of N-protected tetrasubstituted pyrroles has been developed by treating nitroallylic acetates with an amine and a β-keto ester mediated by ceric ammonium nitrate in MeOH. By this method, a diverse array of N-protected pyrrole 2,4-dicarboxylic acid derivatives have been synthesized in 37-76% yield. The reactions proceed smoothly through an interesting SN2' displacement and aromatization process.

原文英語
頁(從 - 到)330-335
頁數6
期刊Asian Journal of Organic Chemistry
2
發行號4
DOIs
出版狀態已發佈 - 2013 一月 1

ASJC Scopus subject areas

  • Organic Chemistry

指紋 深入研究「Three-component Synthesis of Functionalized N-Protected Tetrasubstituted Pyrroles by an Addition-Elimination-Aromatization Process」主題。共同形成了獨特的指紋。

引用此