摘要
A three-component, one-pot, synthesis of N-protected tetrasubstituted pyrroles has been developed by treating nitroallylic acetates with an amine and a β-keto ester mediated by ceric ammonium nitrate in MeOH. By this method, a diverse array of N-protected pyrrole 2,4-dicarboxylic acid derivatives have been synthesized in 37-76% yield. The reactions proceed smoothly through an interesting SN2' displacement and aromatization process.
原文 | 英語 |
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頁(從 - 到) | 330-335 |
頁數 | 6 |
期刊 | Asian Journal of Organic Chemistry |
卷 | 2 |
發行號 | 4 |
DOIs | |
出版狀態 | 已發佈 - 2013 一月 1 |
ASJC Scopus subject areas
- Organic Chemistry