Theory of myelin coiling

J. R. Huang*

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

13 引文 斯高帕斯(Scopus)

摘要

A new model is proposed to explain coiling of myelins composed of fluid bilayers. This model allows the constituent bilayer cylinders of a myelin to be non-coaxial and the bilayer lateral tension to vary from bilayer to bilayer. The calculations show that a myelin would bend or coil to lower its free energy when the bilayer lateral tension is sufficiently large. From a mechanical point of view, the proposed coiling mechanism is analogous to the classical Euler buckling of a thin elastic rod under axial compression. The analysis of a simple two-bilayer case suggests that a bilayer lateral tension of about 1 dyne/cm can easily induce coiling of myelins of typical lipid bilayers. This model signifies the importance of bilayer lateral tension in determining the morphology of myelinic structures.

原文英語
頁(從 - 到)399-412
頁數14
期刊European Physical Journal E
19
發行號4
DOIs
出版狀態已發佈 - 2006 4月
對外發佈

ASJC Scopus subject areas

  • 生物技術
  • 生物物理學
  • 化學 (全部)
  • 材料科學(全部)
  • 表面和介面

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