The effect of covalent immobilization of sialic acid on the removal of lipopolysaccharide and reactive oxygen species for polyethylene terephthalate

Jung Jhih Chang, Po Ju Lin, Yen Hsien Lee, Ming Chien Yang, Chiang-Ting Chien

研究成果: 雜誌貢獻文章

2 引文 (Scopus)

摘要

Polyethylene terephthalate (PET) was aminolyzed with 1,6-diaminohexane (DAH) and then sialic acid (NANA) was immobilized via amidation onto the surface. The surface concentration of NANA was determined by 2-thiobarbituric acid (TBA) test. The hemocompatibility of the resulting PET fabrics was evaluated based on complete blood count (CBC), coagulating times, and protein adsorption. The ability to remove lipopolysaccharide (LPS) was also determined. In addition, the effect of contacting NANA-immobilizing PET on the suppression of reactive oxygen species (ROS) production was measured by the chemiluminescence (CL) method. The results show that by immobilizing NANA onto PET, the adhesion of platelet (PLt) was reduced, and oxidative stress was suppressed. The level of LPS was also greatly reduced.

原文英語
頁(從 - 到)1872-1878
頁數7
期刊Polymers for Advanced Technologies
22
發行號12
DOIs
出版狀態已發佈 - 2011 十二月 1

指紋

Polyethylene Terephthalates
N-Acetylneuraminic Acid
Polyethylene terephthalates
Lipopolysaccharides
Reactive Oxygen Species
1,6-diaminohexane
Oxygen
Acids
Oxidative stress
Chemiluminescence
Platelets
Blood
Adhesion
Proteins
Adsorption

ASJC Scopus subject areas

  • Polymers and Plastics

引用此文

The effect of covalent immobilization of sialic acid on the removal of lipopolysaccharide and reactive oxygen species for polyethylene terephthalate. / Chang, Jung Jhih; Lin, Po Ju; Lee, Yen Hsien; Yang, Ming Chien; Chien, Chiang-Ting.

於: Polymers for Advanced Technologies, 卷 22, 編號 12, 01.12.2011, p. 1872-1878.

研究成果: 雜誌貢獻文章

@article{ec326737f02743beb6f6966364c94311,
title = "The effect of covalent immobilization of sialic acid on the removal of lipopolysaccharide and reactive oxygen species for polyethylene terephthalate",
abstract = "Polyethylene terephthalate (PET) was aminolyzed with 1,6-diaminohexane (DAH) and then sialic acid (NANA) was immobilized via amidation onto the surface. The surface concentration of NANA was determined by 2-thiobarbituric acid (TBA) test. The hemocompatibility of the resulting PET fabrics was evaluated based on complete blood count (CBC), coagulating times, and protein adsorption. The ability to remove lipopolysaccharide (LPS) was also determined. In addition, the effect of contacting NANA-immobilizing PET on the suppression of reactive oxygen species (ROS) production was measured by the chemiluminescence (CL) method. The results show that by immobilizing NANA onto PET, the adhesion of platelet (PLt) was reduced, and oxidative stress was suppressed. The level of LPS was also greatly reduced.",
keywords = "Hemocompatibility, Lipopolysaccharide, Polyethylene terephthalate, Reactive oxygen species (ROS), Sialic acid",
author = "Chang, {Jung Jhih} and Lin, {Po Ju} and Lee, {Yen Hsien} and Yang, {Ming Chien} and Chiang-Ting Chien",
year = "2011",
month = "12",
day = "1",
doi = "10.1002/pat.1686",
language = "English",
volume = "22",
pages = "1872--1878",
journal = "Polymers for Advanced Technologies",
issn = "1042-7147",
publisher = "John Wiley and Sons Ltd",
number = "12",

}

TY - JOUR

T1 - The effect of covalent immobilization of sialic acid on the removal of lipopolysaccharide and reactive oxygen species for polyethylene terephthalate

AU - Chang, Jung Jhih

AU - Lin, Po Ju

AU - Lee, Yen Hsien

AU - Yang, Ming Chien

AU - Chien, Chiang-Ting

PY - 2011/12/1

Y1 - 2011/12/1

N2 - Polyethylene terephthalate (PET) was aminolyzed with 1,6-diaminohexane (DAH) and then sialic acid (NANA) was immobilized via amidation onto the surface. The surface concentration of NANA was determined by 2-thiobarbituric acid (TBA) test. The hemocompatibility of the resulting PET fabrics was evaluated based on complete blood count (CBC), coagulating times, and protein adsorption. The ability to remove lipopolysaccharide (LPS) was also determined. In addition, the effect of contacting NANA-immobilizing PET on the suppression of reactive oxygen species (ROS) production was measured by the chemiluminescence (CL) method. The results show that by immobilizing NANA onto PET, the adhesion of platelet (PLt) was reduced, and oxidative stress was suppressed. The level of LPS was also greatly reduced.

AB - Polyethylene terephthalate (PET) was aminolyzed with 1,6-diaminohexane (DAH) and then sialic acid (NANA) was immobilized via amidation onto the surface. The surface concentration of NANA was determined by 2-thiobarbituric acid (TBA) test. The hemocompatibility of the resulting PET fabrics was evaluated based on complete blood count (CBC), coagulating times, and protein adsorption. The ability to remove lipopolysaccharide (LPS) was also determined. In addition, the effect of contacting NANA-immobilizing PET on the suppression of reactive oxygen species (ROS) production was measured by the chemiluminescence (CL) method. The results show that by immobilizing NANA onto PET, the adhesion of platelet (PLt) was reduced, and oxidative stress was suppressed. The level of LPS was also greatly reduced.

KW - Hemocompatibility

KW - Lipopolysaccharide

KW - Polyethylene terephthalate

KW - Reactive oxygen species (ROS)

KW - Sialic acid

UR - http://www.scopus.com/inward/record.url?scp=82155178876&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=82155178876&partnerID=8YFLogxK

U2 - 10.1002/pat.1686

DO - 10.1002/pat.1686

M3 - Article

AN - SCOPUS:82155178876

VL - 22

SP - 1872

EP - 1878

JO - Polymers for Advanced Technologies

JF - Polymers for Advanced Technologies

SN - 1042-7147

IS - 12

ER -