@article{f0ca61c29e374c12b851b3e09916e696,
title = "The combination of domino process and kinetic resolution: Organocatalytic synthesis of functionalised cyclopentenes by sequential S N2′- Michael reaction",
abstract = "An interesting combination of organocatalytic cascade reaction and kinetic resolution was developed for the synthesis of functionalised cyclopentenes by sequential S N2′-Michael process. Treatment of the racemic nitroallylic acetates with glutaraldehyde in the presence of diphenylprolinol silyl ether to give tetrasubstituted cyclopentenes with high to excellent stereoselectivities (up to 96% ee and 12:1 dr). The less reactive enantiomeric substrates were generally recovered with good to excellent optical purities (up to 99% ee).",
keywords = "Cascade, Cyclopentene, Kinetic resolution, Michael reaction, Organocatalysis",
author = "Yeh, {Lun Fu} and Shaik Anwar and Kwunmin Chen",
note = "Funding Information: We thank the National Science Council of the Republic of China ( NSC 99-2113-M-003-002-MY3 and NSC 99-2119-M-003-001-MY2 ) and National Taiwan Normal University ( 100-D-06 ) for financial support of this work. ",
year = "2012",
month = sep,
day = "9",
doi = "10.1016/j.tet.2012.06.085",
language = "English",
volume = "68",
pages = "7317--7321",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Limited",
number = "36",
}