TY - JOUR
T1 - The bi-metallic MOF-919 (Fe-Cu) nanozyme capable of bifunctional enzyme-mimicking catalytic activity
AU - Kulandaivel, Sivasankar
AU - Lin, Chia Her
AU - Yeh, Yi Chun
N1 - Publisher Copyright:
© The Royal Society of Chemistry.
PY - 2022/1/14
Y1 - 2022/1/14
N2 - In this study, we report on a bi-metal organic framework, MOF-919 (Fe-Cu), capable of bifunctional-enzyme mimicking activity with oxidase- and peroxidase-like activities. The catalytic activities were examined by using o-phenylenediamine (OPD) as a chromogenic substrate to study oxidase- and peroxidase-like mimetics. Based on our findings, we developed a simple epinephrine colorimetric biosensor with a broad linear range (1-100 μM) and a low detection limit (0.298 μM). This approach provides evidence for transition metal-based pristine bi-metallic MOFs capable of reproducing both oxidase-peroxidase properties, which could be applied as new nanosensors.
AB - In this study, we report on a bi-metal organic framework, MOF-919 (Fe-Cu), capable of bifunctional-enzyme mimicking activity with oxidase- and peroxidase-like activities. The catalytic activities were examined by using o-phenylenediamine (OPD) as a chromogenic substrate to study oxidase- and peroxidase-like mimetics. Based on our findings, we developed a simple epinephrine colorimetric biosensor with a broad linear range (1-100 μM) and a low detection limit (0.298 μM). This approach provides evidence for transition metal-based pristine bi-metallic MOFs capable of reproducing both oxidase-peroxidase properties, which could be applied as new nanosensors.
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U2 - 10.1039/d1cc05908d
DO - 10.1039/d1cc05908d
M3 - Article
C2 - 34913054
AN - SCOPUS:85122928804
SN - 1359-7345
VL - 58
SP - 569
EP - 572
JO - Chemical Communications
JF - Chemical Communications
IS - 4
ER -