摘要
Addition of α- and β-amino acid derivatives to the cobalt stabilized propargylic cation 2 gives dicobalthexacarbonyl complexes with an amino acid derivative at the propargyl position. Oxidation of the resulting complexes with Fe(III) produces propargyl amines 4. Intramolecular cyclization of 4 with LDA followed by oxidation of the crude product with DDQ affords pyrrole derivatives as the major products.
原文 | 英語 |
---|---|
頁(從 - 到) | 2823-2826 |
頁數 | 4 |
期刊 | Tetrahedron Letters |
卷 | 36 |
發行號 | 16 |
DOIs | |
出版狀態 | 已發佈 - 1995 四月 17 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry