Synthesis of perhydroisoquinoline derivatives mediated by (η6-arene)Cr(CO)3 complexes

Ming Chang P. Yeh, Chong Nan Chuang, Chun Hsiang Yiu

研究成果: 雜誌貢獻期刊論文同行評審

6 引文 斯高帕斯(Scopus)

摘要

Reaction of lithium hexamethyldisilazide (LHMDS) with (η6-arene)Cr(CO)3 complexes bearing a β-alaninenitrile moiety gives tetrahydroisoquinoline derivatives as the major products after oxidation of the reaction intermediate, whereas protonation of the reaction intermediates produces hexahydroisoquinoline as the major products.

原文英語
頁(從 - 到)7387-7390
頁數4
期刊Tetrahedron Letters
38
發行號42
DOIs
出版狀態已發佈 - 1997 10月 20

ASJC Scopus subject areas

  • 生物化學
  • 藥物發現
  • 有機化學

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