Synthesis of indolylquinolines, indolylacridines, and indolylcyclopenta[b] quinolines from the Baylis-Hillman adducts: An in situ [1,3]-sigmatropic rearrangement of an indole nucleus to access indolylacridines and indolylcyclopenta[b]quinolines

Chintakunta Ramesh, Po Min Lei, Donala Janreddy, Veerababurao Kavala, Chun Wei Kuo, Ching Fa Yao

研究成果: 雜誌貢獻期刊論文同行評審

19 引文 斯高帕斯(Scopus)

摘要

A simple and easy route to the synthesis of a variety of structurally diverse indolylquinolines, indolylacridines, and indolylcyclopenta[b]quinoline derivatives via the reductive cyclization of C-alkylated indole derivatives, derived from acyclic as well as cyclic Baylis-Hillman adducts with indoles, is described. An unusual in situ [1,3]-sigmatropic rearrangement of the indole nucleus was observed during the reductive cyclicization of α- regioselective B-H adducts containing indoles to produce indolylacridines and indolylcyclopenta[b]quinoline derivatives.

原文英語
頁(從 - 到)8451-8464
頁數14
期刊Journal of Organic Chemistry
77
發行號19
DOIs
出版狀態已發佈 - 2012 十月 5

ASJC Scopus subject areas

  • Organic Chemistry

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