Synthesis of Functionalized Benzofurans from para-Quinone Methides via Phospha-1,6-Addition/ O-Acylation/Wittig Pathway

Yan Cheng Liou; Praneeth Karanam; Yeong Jiunn Jang; Wenwei Lin

doi:10.1021/acs.orglett.9b03001

Synthesis of Functionalized Benzofurans from para-Quinone Methides via Phospha-1,6-Addition/ O-Acylation/Wittig Pathway

Yan Cheng Liou
, Praneeth Karanam
, Yeong Jiunn Jang
, Wenwei Lin^*

^*此作品的通信作者

化學系

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

34 引文斯高帕斯（Scopus）

摘要

An efficient synthesis of functionalized benzofurans is achieved under mild and metal-free conditions from stable para-quinone methides by treatment with phosphine, acyl chloride, and a base. This one-pot phospha-1,6-addition/O-acylation/Wittig reaction is also demonstrated under catalytic conditions with similar efficacy.

原文	英語
頁（從 - 到）	8008-8012
頁數	5
期刊	Organic Letters
卷	21
發行號	19
DOIs	https://doi.org/10.1021/acs.orglett.9b03001
出版狀態	已發佈 - 2019 10月 4

ASJC Scopus subject areas

生物化學
物理與理論化學
有機化學

存取文件

10.1021/acs.orglett.9b03001

其它文件與鏈接

CCDC 1943703: Experimental Crystal Structure Determination
Liou, Y.-C. (Contributor), Karanam, P. (Contributor), Jang, Y.-J. (Contributor) & Lin, W. (Contributor), Unknown Publisher, 2019
DOI: 10.5517/ccdc.csd.cc237l32, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc237l32&sid=DataCite
資料集: Dataset
CCDC 1952659: Experimental Crystal Structure Determination
Liou, Y.-C. (Contributor), Karanam, P. (Contributor), Jang, Y.-J. (Contributor) & Lin, W. (Contributor), Unknown Publisher, 2019
DOI: 10.5517/ccdc.csd.cc23jx0l, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc23jx0l&sid=DataCite
資料集: Dataset

引用此

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abstract = "An efficient synthesis of functionalized benzofurans is achieved under mild and metal-free conditions from stable para-quinone methides by treatment with phosphine, acyl chloride, and a base. This one-pot phospha-1,6-addition/O-acylation/Wittig reaction is also demonstrated under catalytic conditions with similar efficacy.",

author = "Liou, \{Yan Cheng\} and Praneeth Karanam and Jang, \{Yeong Jiunn\} and Wenwei Lin",

note = "Publisher Copyright: Copyright {\textcopyright} 2019 American Chemical Society.",

year = "2019",

month = oct,

day = "4",

doi = "10.1021/acs.orglett.9b03001",

language = "English",

volume = "21",

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journal = "Organic Letters",

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T1 - Synthesis of Functionalized Benzofurans from para-Quinone Methides via Phospha-1,6-Addition/ O-Acylation/Wittig Pathway

AU - Liou, Yan Cheng

AU - Karanam, Praneeth

AU - Jang, Yeong Jiunn

AU - Lin, Wenwei

PY - 2019/10/4

Y1 - 2019/10/4

N2 - An efficient synthesis of functionalized benzofurans is achieved under mild and metal-free conditions from stable para-quinone methides by treatment with phosphine, acyl chloride, and a base. This one-pot phospha-1,6-addition/O-acylation/Wittig reaction is also demonstrated under catalytic conditions with similar efficacy.

AB - An efficient synthesis of functionalized benzofurans is achieved under mild and metal-free conditions from stable para-quinone methides by treatment with phosphine, acyl chloride, and a base. This one-pot phospha-1,6-addition/O-acylation/Wittig reaction is also demonstrated under catalytic conditions with similar efficacy.

UR - https://www.scopus.com/pages/publications/85072945679

UR - https://www.scopus.com/pages/publications/85072945679#tab=citedBy

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M3 - Article

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AN - SCOPUS:85072945679

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JO - Organic Letters

JF - Organic Letters

IS - 19

ER -

Synthesis of Functionalized Benzofurans from para-Quinone Methides via Phospha-1,6-Addition/ O-Acylation/Wittig Pathway

摘要

ASJC Scopus subject areas

存取文件

其它文件與鏈接

指紋

資料集

CCDC 1943703: Experimental Crystal Structure Determination

CCDC 1952659: Experimental Crystal Structure Determination

引用此