Synthesis of 2,3,5,6-tetrahydro-1-alkyl/aryl-1H-benzo[f]chromen-3-ol derivatives from β-tetralones and α,β-unsaturated aldehydes

Jung Hsuan Chen, Chihliang Chang, Hui Ju Chang, Kwunmin Chen

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)

摘要

Organocatalytic domino Michael-hemiacetalization of β-tetralones with α,β-unsaturated aldehydes is presented. Treatment of β-tetralones with α,β-unsaturated aldehydes in the presence of diphenylprolinol silyl ether gave 2,3,5,6-tetrahydro-1-alkyl/aryl-1H-benzo[f] chromen-3-ol derivatives with high to excellent chemical yields (50-99%) and high levels of enantioselectivities (up to 96% ee).

原文英語
頁(從 - 到)7510-7516
頁數7
期刊Organic and Biomolecular Chemistry
9
發行號21
DOIs
出版狀態已發佈 - 2011 十一月 7

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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