@article{358358072da54f339781a3fcf4ae4aac,
title = "Synthesis and structure-activity relationships of novel furazan-3,4-diamide analogs as potent anti-cancer agents",
abstract = "This study describes the synthesis and structure-activity relationships of a series of furazan-3,4-diamide analogs. 1,2,5-Oxadiazole ring and electron-withdrawing substituent on the phenyl ring are proposed to be the important elements which contribute to a significant extent maximal potency of anti-proliferation effect.",
keywords = "Anti-cancer agents, Drug discovery, Structure-activity relationship, Synthesis",
author = "Li, {Wen Shan} and More, {Shivaji V.} and Wang, {Chie Hong} and Jen, {Ya Ching} and Yao, {Ching Fa} and Wang, {Tein Fu} and Hung, {Chin Chun} and Jao, {Shu Chuan}",
note = "Funding Information: We are grateful to Ping-Yu Lin and Dr. Mei-Chun Tseng for assistance with mass spectrometry. We thank the National Science Council ( NSC 95-2113-M-001-018-MY3 ) and Academia Sinica (program project AS-95-TP-AB1) for financial support. ",
year = "2010",
month = feb,
day = "1",
doi = "10.1016/j.bmcl.2009.12.017",
language = "English",
volume = "20",
pages = "1148--1152",
journal = "Bioorganic and Medicinal Chemistry Letters",
issn = "0960-894X",
publisher = "Elsevier Limited",
number = "3",
}
