Surface plasmons coupled two-dimensional photonic crystal biosensors for Epstein-Barr virus protein detection

Yung Tsan Chen, Yu Yang Liao, Chien Chun Chen, Hui Hsin Hsiao, Jian Jang Huang

研究成果: 雜誌貢獻期刊論文同行評審

6 引文 斯高帕斯(Scopus)

摘要

The fundamental detection scheme of typical grating or photonic crystal (PhC) sensors relies on the correlation of the diffraction behaviors with the refractive index of target analyte. For biomaterial detection, a thin gold film is usually deposited on the sensor surface so that cross linkers can be anchored before functionalizing the device. The nanoscale metallic film suggests plasmonic resonances play a critical role in light-matter interaction. In this work, we demonstrated a compact two-dimensional (2D) hexagonal PhC biosensor with thin gold film coating. In such a device, surface plasmon polariton (SPP) on the metal structure and phase matching of optical wave with the PhC are considered when analyzing light-biomaterial interaction on the detector. Using Epstein-Barr nuclear antigen-1 (EBNA-1) antibody as an example, protein sensing along different lattice orientations of the PhC biosensor was investigated. Based on the dispersion relationship and phase matching conditions, we unravel the mechanisms involved in the wavelength shifts and sensitivities. The simulation results verify the phenomenon of tighter spatial confinement and higher local field intensity from the SPP, which helps detecting small variations of the refractive index on the sensor surface.

原文英語
頁(從 - 到)81-88
頁數8
期刊Sensors and Actuators, B: Chemical
291
DOIs
出版狀態已發佈 - 2019 七月 15

ASJC Scopus subject areas

  • 電子、光磁材料
  • 儀器
  • 凝聚態物理學
  • 表面、塗料和薄膜
  • 金屬和合金
  • 電氣與電子工程
  • 材料化學

指紋

深入研究「Surface plasmons coupled two-dimensional photonic crystal biosensors for Epstein-Barr virus protein detection」主題。共同形成了獨特的指紋。

引用此