Study on the synthesis of 6-alkylaminouridines via the nucleophilic aromatic substitution reaction of 6-cyanouridine derivatives

Jian Bang Lin, Jhih Li He, Yu Chiao Shih, Tun Cheng Chien

研究成果: 雜誌貢獻期刊論文同行評審

2 引文 斯高帕斯(Scopus)

摘要

6-Cyanouracil derivatives underwent direct substitution reactions with selective primary amines in the presence of N,N-dimethylaminopyridine as a catalyst to give the corresponding 6-alkylaminouracils. This reaction provides a facile access to versatile 6-alkylaminouridine derivatives.

原文英語
頁(從 - 到)3969-3972
頁數4
期刊Tetrahedron Letters
52
發行號31
DOIs
出版狀態已發佈 - 2011 八月 3

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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