Study of γ-Fe2O3/Au core/shell nanoparticles as the contrast agent for high-Tc SQUID-based low field nuclear magnetic resonance

Kuen Lin Chen, Yao Wei Yeh, Shu Hsien Liao, Chiu Hsien Wu, Li Min Wang

研究成果: 書貢獻/報告類型會議論文篇章

2 引文 斯高帕斯(Scopus)

摘要

To improve the image contrast, the so-called contrast agents (CAs) are often used in magnetic resonance image (MRI). CAs are generally paramagnetic or superparamagnetic nanoparticle suspensions. To increase the applicability of low field nuclear magnetic resonance (LFNMR) or LFMRI system, CAs also have been introduced to enhance the image contrast. In this work, we synthesized the γ-Fe2O3/Au core/shell (γ-Fe2O3@Au) nanoparticle and applied it to a homemade high-Tc SQUID-based LFNMR system to study the characteristics of γ-Fe2O3@Au nanoparticle as the contrast agent for the LFNMR system. The average hydrodynamic sizes of the synthesized γ-Fe2O3@Au nanoparticles are 28.38 ± 6.26 nm in diameter. The γ-Fe2O3@Au nanoparticles exhibit a characteristic absorption peak at 536 nm from the contribution of localized surface plasmon resonance of Au shell. The spin-lattice relaxation rate, 1/T1, and the spin-spin relaxation rate, 1/T2, varied with the concentration of γ-Fe2O3@Au nanoparticle. Compared with the data measured in high field (7 Tesla), we found that the γ-Fe2O3@Au nanoparticle is a promising T1-relaxing CA for LFNMR.

原文英語
主出版物標題16th International Conference on Nanotechnology - IEEE NANO 2016
發行者Institute of Electrical and Electronics Engineers Inc.
頁面585-586
頁數2
ISBN(電子)9781509039142
DOIs
出版狀態已發佈 - 2016 11月 21
事件16th IEEE International Conference on Nanotechnology - IEEE NANO 2016 - Sendai, 日本
持續時間: 2016 8月 222016 8月 25

出版系列

名字16th International Conference on Nanotechnology - IEEE NANO 2016

會議

會議16th IEEE International Conference on Nanotechnology - IEEE NANO 2016
國家/地區日本
城市Sendai
期間2016/08/222016/08/25

ASJC Scopus subject areas

  • 電子、光磁材料
  • 原子與分子物理與光學

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