Study of γ-Fe2O3/Au core/shell nanoparticles as the contrast agent for high-Tc SQUID-based low field nuclear magnetic resonance

Kuen Lin Chen, Yao Wei Yeh, Shu Hsien Liao, Chiu Hsien Wu, Li Min Wang

    研究成果: 書貢獻/報告類型會議貢獻

    1 引文 斯高帕斯(Scopus)

    摘要

    To improve the image contrast, the so-called contrast agents (CAs) are often used in magnetic resonance image (MRI). CAs are generally paramagnetic or superparamagnetic nanoparticle suspensions. To increase the applicability of low field nuclear magnetic resonance (LFNMR) or LFMRI system, CAs also have been introduced to enhance the image contrast. In this work, we synthesized the γ-Fe2O3/Au core/shell (γ-Fe2O3@Au) nanoparticle and applied it to a homemade high-Tc SQUID-based LFNMR system to study the characteristics of γ-Fe2O3@Au nanoparticle as the contrast agent for the LFNMR system. The average hydrodynamic sizes of the synthesized γ-Fe2O3@Au nanoparticles are 28.38 ± 6.26 nm in diameter. The γ-Fe2O3@Au nanoparticles exhibit a characteristic absorption peak at 536 nm from the contribution of localized surface plasmon resonance of Au shell. The spin-lattice relaxation rate, 1/T1, and the spin-spin relaxation rate, 1/T2, varied with the concentration of γ-Fe2O3@Au nanoparticle. Compared with the data measured in high field (7 Tesla), we found that the γ-Fe2O3@Au nanoparticle is a promising T1-relaxing CA for LFNMR.

    原文英語
    主出版物標題16th International Conference on Nanotechnology - IEEE NANO 2016
    發行者Institute of Electrical and Electronics Engineers Inc.
    頁面585-586
    頁數2
    ISBN(電子)9781509039142
    DOIs
    出版狀態已發佈 - 2016 十一月 21
    事件16th IEEE International Conference on Nanotechnology - IEEE NANO 2016 - Sendai, 日本
    持續時間: 2016 八月 222016 八月 25

    出版系列

    名字16th International Conference on Nanotechnology - IEEE NANO 2016

    會議

    會議16th IEEE International Conference on Nanotechnology - IEEE NANO 2016
    國家日本
    城市Sendai
    期間16/8/2216/8/25

      指紋

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Atomic and Molecular Physics, and Optics

    引用此

    Chen, K. L., Yeh, Y. W., Liao, S. H., Wu, C. H., & Wang, L. M. (2016). Study of γ-Fe2O3/Au core/shell nanoparticles as the contrast agent for high-Tc SQUID-based low field nuclear magnetic resonance. 於 16th International Conference on Nanotechnology - IEEE NANO 2016 (頁 585-586). [7751445] (16th International Conference on Nanotechnology - IEEE NANO 2016). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NANO.2016.7751445