TY - JOUR
T1 - Stimulus driver for epilepsy seizure suppression with adaptive loading impedance
AU - Ker, Ming Dou
AU - Lin, Chun Yu
AU - Chen, Wei Ling
PY - 2011/12
Y1 - 2011/12
N2 - A stimulus driver circuit for a micro-stimulator used in an implantable device is presented in this paper. For epileptic seizure control, the target of the driver was to output 30 νA stimulus currents when the electrode impedance varied between 20 and 200 kΩ. The driver, which consisted of the output stage, control block and adaptor, was integrated in a single chip. The averaged power consumption of the stimulus driver was 0.24-0.56 mW at 800 Hz stimulation rate. Fabricated in a 0.35 νm 3.3 V/24 V CMOS process and applied to a closed-loop epileptic seizure monitoring and controlling system, the proposed design has been successfully verified in the experimental results of Long-Evans rats with epileptic seizures.
AB - A stimulus driver circuit for a micro-stimulator used in an implantable device is presented in this paper. For epileptic seizure control, the target of the driver was to output 30 νA stimulus currents when the electrode impedance varied between 20 and 200 kΩ. The driver, which consisted of the output stage, control block and adaptor, was integrated in a single chip. The averaged power consumption of the stimulus driver was 0.24-0.56 mW at 800 Hz stimulation rate. Fabricated in a 0.35 νm 3.3 V/24 V CMOS process and applied to a closed-loop epileptic seizure monitoring and controlling system, the proposed design has been successfully verified in the experimental results of Long-Evans rats with epileptic seizures.
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U2 - 10.1088/1741-2560/8/6/066008
DO - 10.1088/1741-2560/8/6/066008
M3 - Article
C2 - 22027449
AN - SCOPUS:81855200022
SN - 1741-2560
VL - 8
JO - Journal of Neural Engineering
JF - Journal of Neural Engineering
IS - 6
M1 - 066008
ER -