Stereoselective three-component synthesis of trans-endo-decahydroquinolin- 4-one derivatives from aldehydes, aniline, and acetylcyclohexene

Chunchi Lin; Hulin Fang; Zhijay Tu; Ju Tsung Liu; Ching Fa Yao

doi:10.1021/jo060992c

Stereoselective three-component synthesis of trans-endo-decahydroquinolin- 4-one derivatives from aldehydes, aniline, and acetylcyclohexene

Chunchi Lin
, Hulin Fang
, Zhijay Tu
, Ju Tsung Liu
, Ching Fa Yao^*

^*此作品的通信作者

化學系

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

38 引文斯高帕斯（Scopus）

摘要

The diastereoselective synthesis of trans-endo-decahydroquinolin-4-one (4) via a three-component reaction of aldehydes (1), anilines (2), and 1-acetylcyclohexene (3) in the presence of iodine in a one-pot reaction at room temperature is described. The short reaction time, easy workup, excellent yield, and mild reaction conditions make this novel annulation strategy both practical and attractive.

原文	英語
頁（從 - 到）	6588-6591
頁數	4
期刊	Journal of Organic Chemistry
卷	71
發行號	17
DOIs	https://doi.org/10.1021/jo060992c
出版狀態	已發佈 - 2006 8月 18

ASJC Scopus subject areas

有機化學

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10.1021/jo060992c

其它文件與鏈接

CCDC 602079: Experimental Crystal Structure Determination
Lin, C. (Creator), Fang, H. (Creator), Tu, Z. (Creator), Liu, J.-T. (Creator) & Yao, C.-F. (Creator), Unknown Publisher, 2006
DOI: 10.5517/ccn6hx7, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccn6hx7&sid=DataCite
資料集: Dataset
CCDC 602081: Experimental Crystal Structure Determination
Lin, C. (Creator), Fang, H. (Creator), Tu, Z. (Creator), Liu, J.-T. (Creator) & Yao, C.-F. (Creator), Unknown Publisher, 2006
DOI: 10.5517/ccn6hz9, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccn6hz9&sid=DataCite
資料集: Dataset
CCDC 602080: Experimental Crystal Structure Determination
Lin, C. (Creator), Fang, H. (Creator), Tu, Z. (Creator), Liu, J.-T. (Creator) & Yao, C.-F. (Creator), Unknown Publisher, 2006
DOI: 10.5517/ccn6hy8, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccn6hy8&sid=DataCite
資料集: Dataset

引用此

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abstract = "The diastereoselective synthesis of trans-endo-decahydroquinolin-4-one (4) via a three-component reaction of aldehydes (1), anilines (2), and 1-acetylcyclohexene (3) in the presence of iodine in a one-pot reaction at room temperature is described. The short reaction time, easy workup, excellent yield, and mild reaction conditions make this novel annulation strategy both practical and attractive.",

author = "Chunchi Lin and Hulin Fang and Zhijay Tu and Liu, \{Ju Tsung\} and Yao, \{Ching Fa\}",

year = "2006",

month = aug,

day = "18",

doi = "10.1021/jo060992c",

language = "English",

volume = "71",

pages = "6588--6591",

journal = "Journal of Organic Chemistry",

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T1 - Stereoselective three-component synthesis of trans-endo-decahydroquinolin- 4-one derivatives from aldehydes, aniline, and acetylcyclohexene

AU - Lin, Chunchi

AU - Fang, Hulin

AU - Tu, Zhijay

AU - Liu, Ju Tsung

AU - Yao, Ching Fa

PY - 2006/8/18

Y1 - 2006/8/18

N2 - The diastereoselective synthesis of trans-endo-decahydroquinolin-4-one (4) via a three-component reaction of aldehydes (1), anilines (2), and 1-acetylcyclohexene (3) in the presence of iodine in a one-pot reaction at room temperature is described. The short reaction time, easy workup, excellent yield, and mild reaction conditions make this novel annulation strategy both practical and attractive.

AB - The diastereoselective synthesis of trans-endo-decahydroquinolin-4-one (4) via a three-component reaction of aldehydes (1), anilines (2), and 1-acetylcyclohexene (3) in the presence of iodine in a one-pot reaction at room temperature is described. The short reaction time, easy workup, excellent yield, and mild reaction conditions make this novel annulation strategy both practical and attractive.

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UR - https://www.scopus.com/pages/publications/33747437605#tab=citedBy

U2 - 10.1021/jo060992c

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M3 - Article

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AN - SCOPUS:33747437605

SN - 0022-3263

VL - 71

SP - 6588

EP - 6591

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 17

ER -

Stereoselective three-component synthesis of trans-endo-decahydroquinolin- 4-one derivatives from aldehydes, aniline, and acetylcyclohexene

摘要

ASJC Scopus subject areas

存取文件

其它文件與鏈接

指紋

資料集

CCDC 602079: Experimental Crystal Structure Determination

CCDC 602081: Experimental Crystal Structure Determination

CCDC 602080: Experimental Crystal Structure Determination

引用此