摘要
The diastereoselective synthesis of trans-endo-decahydroquinolin-4-one (4) via a three-component reaction of aldehydes (1), anilines (2), and 1-acetylcyclohexene (3) in the presence of iodine in a one-pot reaction at room temperature is described. The short reaction time, easy workup, excellent yield, and mild reaction conditions make this novel annulation strategy both practical and attractive.
| 原文 | 英語 |
|---|---|
| 頁（從 - 到） | 6588-6591 |
| 頁數 | 4 |
| 期刊 | Journal of Organic Chemistry |
| 卷 | 71 |
| 發行號 | 17 |
| DOIs | |
| 出版狀態 | 已發佈 - 2006 8月 18 |
ASJC Scopus subject areas
- 有機化學
指紋
深入研究「Stereoselective three-component synthesis of trans-endo-decahydroquinolin- 4-one derivatives from aldehydes, aniline, and acetylcyclohexene」主題。共同形成了獨特的指紋。資料集
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CCDC 622846: Experimental Crystal Structure Determination
Lin, C. (Creator), Fang, H. (Creator), Tu, Z. (Creator), Liu, J. (Creator) & Yao, C. (Creator), Unknown Publisher, 2006
DOI: 10.5517/ccnx3tg, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccnx3tg&sid=DataCite
資料集: Dataset
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CCDC 602079: Experimental Crystal Structure Determination
Lin, C. (Creator), Fang, H. (Creator), Tu, Z. (Creator), Liu, J. (Creator) & Yao, C. (Creator), Unknown Publisher, 2006
DOI: 10.5517/ccn6hx7, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccn6hx7&sid=DataCite
資料集: Dataset
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CCDC 602078: Experimental Crystal Structure Determination
Lin, C. (Creator), Fang, H. (Creator), Tu, Z. (Creator), Liu, J. (Creator) & Yao, C. (Creator), Unknown Publisher, 2006
DOI: 10.5517/ccn6hw6, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccn6hw6&sid=DataCite
資料集: Dataset