Stereoselective three-component synthesis of trans-endo-decahydroquinolin- 4-one derivatives from aldehydes, aniline, and acetylcyclohexene

Chunchi Lin, Hulin Fang, Zhijay Tu, Ju Tsung Liu, Ching Fa Yao

研究成果: 雜誌貢獻文章同行評審

35 引文 斯高帕斯(Scopus)

摘要

The diastereoselective synthesis of trans-endo-decahydroquinolin-4-one (4) via a three-component reaction of aldehydes (1), anilines (2), and 1-acetylcyclohexene (3) in the presence of iodine in a one-pot reaction at room temperature is described. The short reaction time, easy workup, excellent yield, and mild reaction conditions make this novel annulation strategy both practical and attractive.

原文英語
頁(從 - 到)6588-6591
頁數4
期刊Journal of Organic Chemistry
71
發行號17
DOIs
出版狀態已發佈 - 2006 八月 18

ASJC Scopus subject areas

  • Organic Chemistry

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