Stability study for magnetic reagent assaying Hb and HbA1c

Wen Pin Hsieh, J. J. Chieh, C. C. Yang, S. Y. Yang, Po Yu Chen, Yu Hao Huang, Y. W. Hong, H. E. Horng*


研究成果: 雜誌貢獻期刊論文同行評審

1 引文 斯高帕斯(Scopus)


Reagents for magnetically labeled immunoassay on human Hb and human HbA1c have been synthesized. The reagents consist of Fe 3O 4 magnetic particles biofunctionalized with antibodies against Hb and HbA1c. It has been demonstrated that the reagents can be applied to quantitatively detect Hb and HbA1c by using immunomagnetic reduction assay. In addition to characterizing the assay properties, such as the standard curve and the low-detection limit, the stability of reagents is investigated. To do this, the temporal dependence of particle sizes and the bio-activity of reagents are monitored. The results show that the reagents are highly stable when stored at 2-8 °C. This means that the reagents synthesized in this work are promising for practical applications.

頁(從 - 到)147-150
期刊Journal of Magnetism and Magnetic Materials
出版狀態已發佈 - 2013 1月

ASJC Scopus subject areas

  • 電子、光磁材料
  • 凝聚態物理學


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