Signal analysis and liver tumor discrimination by using a high-Tc SQUID-based low-field NMR system in hospital

Shu Hsien Liao, Jen Jie Chieh, Yen Ting Chou, Ming Wei Wang, Hsin Hsien Chen, Kai Wen Huang, Hong-Chang Yang, Herng-Er Horng

研究成果: 雜誌貢獻期刊論文同行評審

摘要

In this paper, a high-Tc SQUID-based nuclear magnetic resonance (NMR) spectrometer was set up in National Taiwan University Hospital to discriminate liver tumor. In order to overcome the surrounding noise, a four-layer Al shielded box and a cylindrical magnetic shield were employed to avoid the electromagnetic noise in the coils part and the SQUID part, respectively. For NMR measurement, the larmor frequency is varying with time due to the variation of static field in hospital. Therefore, the time-domain frequency adjusted average method guided by a fluxgate was used to correct the frequency variation and average the NMR signal in the time domain. For tumor discrimination, the T1 relaxation times of normal tissue and tumor tissue were demonstrated. Our high-Tc SQUID-based low-field MRI system shows the feasibility for biomedical application in a clinic environment.

原文英語
文章編號7012140
期刊IEEE Transactions on Applied Superconductivity
25
發行號3
DOIs
出版狀態已發佈 - 2015 6月 1

ASJC Scopus subject areas

  • 電子、光磁材料
  • 凝聚態物理學
  • 電氣與電子工程

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