Semiautomatic and rapid quantification of heartbeat parameters in Drosophila using optical coherence tomography imaging

Shou Yuan Guo, Fang Tsu Liao, Ming Tsan Su, Cheng Yi Chang, Hong Ren Su, Jyun Cin Huang, Wen Chuan Kuo*

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

7 引文 斯高帕斯(Scopus)

摘要

We report a semiautomatic algorithm that is specialized for rapid analysis of beat-to-beat contraction relaxation parameters of the heart in Drosophila. The presented algorithm adapts the general graph theoretical image segmentation algorithm and a histogram-based thresholding algorithm, which can measure many cardiac parameters, including heart rate, heart period, diastolic and systolic intervals, and end-diastolic and end-systolic areas. Additionally, dynamic cardiac functions, such as arrhythmia index and percent fractional shortening, can be automatically calculated for all the recorded heartbeats over significant periods of time.

原文英語
文章編號026004
期刊Journal of Biomedical Optics
18
發行號2
DOIs
出版狀態已發佈 - 2013 二月

ASJC Scopus subject areas

  • 電子、光磁材料
  • 生物材料
  • 原子與分子物理與光學
  • 生物醫學工程

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