Seed peptide lunasin ameliorates obesity-induced inflammation and regulates immune responses in C57BL/6J mice fed high-fat diet

Agriculture & Biology

• high fat diet 63%
• obesity 61%
• inflammation 53%
• immune response 48%
• interleukin-2 44%
• splenocytes 42%
• peptides 39%
• T-lymphocytes 35%
• macrophages 34%
• mice 33%
• seeds 30%
• chemokine CCL2 30%
• tumor necrosis factors 26%
• immunomodulation 25%
• low fat diet 25%
• chronic diseases 23%
• interleukin-1 23%
• leptin 22%
• interferon-gamma 22%
• interleukin-6 21%
• intraperitoneal injection 21%
• adipose tissue 19%
• malondialdehyde 17%
• cell proliferation 17%
• spleen 16%
• secretion 13%
• phenotype 12%
• cells 12%
• gender 11%
• lipids 10%
• tissues 8%

Medicine & Life Sciences

• Seeds 59%
• High Fat Diet 58%
• Inbred C57BL Mouse 55%
• Obesity 40%
• Peptides 37%
• Interleukin-2 34%
• Inflammation 34%
• Fat-Restricted Diet 24%
• T-Lymphocytes 24%
• Obese Mice 23%
• Th1 Cells 22%
• Immunomodulation 22%
• Chemokine CCL2 21%
• Peritoneal Macrophages 21%
• Immune System Diseases 20%
• Interleukin-1 19%
• Leptin 19%
• Intraperitoneal Injections 19%
• Malondialdehyde 18%
• Interferon-gamma 17%
• Adipose Tissue 16%
• Spleen 15%
• Interleukin-6 15%
• Chronic Disease 14%
• Anti-Inflammatory Agents 14%
• Tumor Necrosis Factor-alpha 13%
• Macrophages 13%
• Cell Proliferation 12%
• Lipids 12%
• Phenotype 11%
• Serum 8%
• In Vitro Techniques 8%

Chemical Compounds

• Leptin 100%
• Chemoattractant 85%
• Intraperitoneal 74%
• Antiinflammatory 55%
• Disorder 50%
• Occurrence in Nature 48%
• Bioactivity 42%
• Lipid 40%
• Peptide 33%