Risk of prostate and bladder cancers in patients with spinal cord injury: A population-based cohort study1

Wen Yuan Lee, Li Min Sun, Cheng Li Lin, Ji An Liang, Yen Jung Chang, Fung Chang Sung, Chia Hung Kao*

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

18 引文 斯高帕斯(Scopus)

摘要

Objective: To evaluate the risk of prostate and bladder cancers in patients with spinal cord injury (SCI). Materials and methods: We used data obtained from the National Health Insurance system of Taiwan for this study. The SCI cohort contained 54,401 patients with SCI, and each patient was randomly frequency matched with 4 people from the general population (without SCI) based on age, sex, and index date. Incidence rates, SCI cohort to non-SCI cohort rate ratios, and hazard ratios were measured to evaluate the cancer risks. Results: Patients with SCI showed a significantly lower risk of developing prostate cancer compared with subjects without SCI (adjusted hazard ratio = 0.73; 95% confidence interval = 0.59, 0.90), after accounting for the competing risk of death. No significant difference in the risk of bladder cancer emerged between the SCI and control groups. Further analyses found a higher spinal level of SCI tended to predict a lower risk for prostate cancer. Conclusions: Patients with SCI incurred a lower risk for prostate cancer compared with people without SCI. The risk for bladder cancer did not differ between people with or without SCI.

原文英語
頁(從 - 到)51.e1-51.e7
期刊Urologic Oncology: Seminars and Original Investigations
32
發行號1
DOIs
出版狀態已發佈 - 2014 一月
對外發佈

ASJC Scopus subject areas

  • 腫瘤科
  • 泌尿科學

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