Rhodium(I)-catalyzed asymmetric addition of organometallic reagents to unsaturated compounds

Hsyueh Liang Wu*, Ping Yu Wu

*此作品的通信作者

研究成果: 書貢獻/報告類型篇章

摘要

The rhodium-catalyzed asymmetric addition reaction of organoboron reagents to a,ß-unsaturated compounds has seen significant growth in the past two decades for their user-friendly reaction conditions, which generally allow the use of water as a cosolvent. This chapter highlights advancements ranging from 2004 to 2017 in this field and organizes the content in terms of the applicable substrates with respect to the chiral ligands. Bis-sulfoxide ligands emerged as one of the privileged ligand family in C-H oxidation reaction by coordinating Pd with sulfur atoms. Ligands with two distinct chelating centers are regarded as hybrid ligands. While dienes generally display greater catalytic activity than phosphorus ligands, the coordinating ability of diene ligands is weaker than that of phosphine-based ones. a,ß-unsaturated esters are generally good reaction partners in the Rh-catalyzed conjugate addition reactions for 1,4-addition products. Nitroolefin compounds are excellent substrates in the rhodium-catalyzed asymmetric conjugate addition reactions as a result of their highly electrophilic nature.

原文英語
主出版物標題Rhodium Catalysis in Organic Synthesis
主出版物子標題Methods and Reactions
發行者wiley
頁面85-116
頁數32
ISBN(電子)9783527811878
ISBN(列印)9783527343645
DOIs
出版狀態已發佈 - 2018 十二月 28

ASJC Scopus subject areas

  • 化學 (全部)

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