Renal R2 chemoreceptor activity is attenuated after back heating in the rat

Ming Shiou Wu, Chiang Ting Chien, Chau Fong Chen*


研究成果: 雜誌貢獻期刊論文同行評審

1 引文 斯高帕斯(Scopus)


Recent study in our laboratory has found that renal afferent nervous activity (RANA) was decreased during and after 42°C back heating (BH). To investigate which renal sensory receptor is influenced during and after BH, a C-shaped glass heating pad (42°C) was used on the skin of the back overlying the kidneys. A single-unit recording was used to identify four types of renal sensory receptors, the R2 chemoreceptor (CR2), arterial mechanoreceptor (MRa), ureteropelvic mechanoreceptor (MRu) and venous mechanoreceptor (MRv) in anesthetized female Wistar rats. Renal cortical microvascular blood flow (CMBF) and urinary water, potassium and sodium output were measured. It was found that CR2 activity was significantly decreased during and after BH, but three types of MRs were not altered. CMBF and urine output were significantly increased during and after BH. It is concluded that the increase in renal hemodynamics by BH may dilute some chemicals in the kidney and decrease the firing rate of R2 chemoreceptors.

頁(從 - 到)101-104
期刊Neuroscience Letters
出版狀態已發佈 - 1997 6月 27

ASJC Scopus subject areas

  • 一般神經科學


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