Relaxation of biofunctionalized magnetic nanoparticles in ultra-low magnetic fields

H. C. Yang, L. L. Chiu, S. H. Liao, H. H. Chen, H. E. Horng, C. W. Liu, C. I. Liu, K. L. Chen, M. J. Chen, L. M. Wang

研究成果: 雜誌貢獻文章同行評審

4 引文 斯高帕斯(Scopus)


In this work, the spin-spin relaxation rate, 1/T2, and spin-lattice relaxation rate, 1/T1, of protons' spins induced by biofunctionalized magnetic nanoparticles and ferrofluids are investigated using a high-Tc superconducting quantum interference device-detected magnetometer in ultra-low fields. The biofunctionalized magnetic nanoparticles are the anti-human C-reactive protein (antiCRP) coated onto dextran-coated superparamagnetic iron oxides Fe3O4, which is labeled as Fe3O4-antiCRP. The ferrofluids are dextran-coated iron oxides. It was found that both 1/T2 and 1/T1 of protons in Fe3O4-antiCRP are enhanced by the presence of magnetic nanoparticles. Additionally, both the 1/T1 and 1/T2 of Fe3O4-antiCRP are close to that of ferrofluids, which are dextran-coated Fe3O4 dispersed in phosphate buffer saline. Characterizing the relaxation of Fe3O4-antiCRP can be useful for biomedical applications.

期刊Journal of Applied Physics
出版狀態已發佈 - 2013 一月 28

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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