Recent developments in Zn-catalyzed asymmetric addition reaction to ketones: Syntheses of chiral tertiary alcohols

Hsyueh Liang Wu; Chiung An Chang; Ping Yu Wu; Biing Jiun Uang

doi:10.1016/j.tetlet.2017.01.034

Recent developments in Zn-catalyzed asymmetric addition reaction to ketones: Syntheses of chiral tertiary alcohols

Hsyueh Liang Wu^*, Chiung An Chang, Ping Yu Wu, Biing Jiun Uang

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化學系

研究成果: 雜誌貢獻 › 回顧評介論文 › 同行評審

14 引文斯高帕斯（Scopus）

摘要

Zn-catalyzed asymmetric alkylation reaction with carbonyl compounds has provided a straightforward method to access enantio-enriched tertiary alcohols. This chiral carbon-carbon bond forming process has attracted great attention in the field of asymmetric synthesis with features of mild reaction conditions, tolerating diverse functional groups and employment of low toxic zinc metal. In this digest, the recent developments of this asymmetric protocol are focused.

原文	英語
頁（從 - 到）	706-710
頁數	5
期刊	Tetrahedron Letters
卷	58
發行號	8
DOIs	https://doi.org/10.1016/j.tetlet.2017.01.034
出版狀態	已發佈 - 2017

ASJC Scopus subject areas

生物化學
藥物發現
有機化學

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10.1016/j.tetlet.2017.01.034

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abstract = "Zn-catalyzed asymmetric alkylation reaction with carbonyl compounds has provided a straightforward method to access enantio-enriched tertiary alcohols. This chiral carbon-carbon bond forming process has attracted great attention in the field of asymmetric synthesis with features of mild reaction conditions, tolerating diverse functional groups and employment of low toxic zinc metal. In this digest, the recent developments of this asymmetric protocol are focused.",

keywords = "Chiral tertiary alcohols, Enantioselective catalysis, Zn-catalyzed asymmetric addition",

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T2 - Syntheses of chiral tertiary alcohols

AU - Wu, Hsyueh Liang

AU - Chang, Chiung An

AU - Wu, Ping Yu

AU - Uang, Biing Jiun

PY - 2017

Y1 - 2017

N2 - Zn-catalyzed asymmetric alkylation reaction with carbonyl compounds has provided a straightforward method to access enantio-enriched tertiary alcohols. This chiral carbon-carbon bond forming process has attracted great attention in the field of asymmetric synthesis with features of mild reaction conditions, tolerating diverse functional groups and employment of low toxic zinc metal. In this digest, the recent developments of this asymmetric protocol are focused.

AB - Zn-catalyzed asymmetric alkylation reaction with carbonyl compounds has provided a straightforward method to access enantio-enriched tertiary alcohols. This chiral carbon-carbon bond forming process has attracted great attention in the field of asymmetric synthesis with features of mild reaction conditions, tolerating diverse functional groups and employment of low toxic zinc metal. In this digest, the recent developments of this asymmetric protocol are focused.

KW - Chiral tertiary alcohols

KW - Enantioselective catalysis

KW - Zn-catalyzed asymmetric addition

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Recent developments in Zn-catalyzed asymmetric addition reaction to ketones: Syntheses of chiral tertiary alcohols

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