Quick screening of true tyrosinase inhibitors from natural products using tyrosinase-immobilized magnetic nanoparticles and a magnetic microplate: Part II melanogenesis bioactivity

Hwei yan Tsai*, Chih Chung Hsieh, Yun Ching Chang, Yi ching Lin, Sung Fang Chen

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

摘要

We previously reported a rapid method for screening true tyrosinase inhibitors. Here, the identified active component from litchi flower extract was further confirmed using a tyrosinase inhibitory assay and inhibitory effects on melanogenesis of murine melanoma B16-F1 cell to prove its bioactivity. This is the first report regarding the inhibitory effect of abscisic acid on melanogenesis. The crude extraction of litchi flower showed some degree of cell toxicity. This report would also like to remind people who want to use crude extraction of herbs to carefully check their toxicological test reports.

原文英語
頁(從 - 到)2290-2293
頁數4
期刊Journal of the Chinese Chemical Society
68
發行號12
DOIs
出版狀態已發佈 - 2021 12月

ASJC Scopus subject areas

  • 化學 (全部)

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