@article{67383f9de4854efd9acde5c1812ca7f5,
title = "Preparation of highly functionalized arylmagnesium reagents by the addition of magnesium phenylselenide to arynes",
abstract = "The described polyfunctional arylmagnesium reagents, resulting from the highly regioselective addition of magnesium phenylselenide to functionalized arynes, can be trapped by a range of electrophiles, yielding polyfunctional selenoethers in 45-85% yields. Furthermore, these Grignard reagents can be used in Negishi cross-coupling reactions with iodoarenes after transmetalation to the corresponding arylzinc compounds, furnishing functionalized biaryl products in 55-73% yields.",
keywords = "Aryne, Organomagnesium reagent, Selenoether",
author = "Wenwei Lin and Florian Ilgen and Paul Knochel",
note = "Funding Information: We thank the Fonds der Chemischen Industrie, the Deutsche Forschungsgemeinschaft (DFG) and Merck Research Laboratories (MSD) for financial support. We also thank Chemetall GmbH (Frankfurt) and BASF AG (Ludwigshafen) for the generous gift of chemicals.",
year = "2006",
month = mar,
day = "20",
doi = "10.1016/j.tetlet.2006.01.071",
language = "English",
volume = "47",
pages = "1941--1944",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "12",
}