Preparation of Furo[3,2-c]coumarins from 3-Cinnamoyl-4-hydroxy-2H-chromen-2-ones and Acyl Chlorides: A Bu3P-Mediated C-Acylation/Cyclization Sequence

Chia Jui Lee, Cheng Che Tsai, Shao Hao Hong, Geng Hua Chang, Mei Chun Yang, Lennart Möhlmann, Wenwei Lin*

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

35 引文 斯高帕斯(Scopus)

摘要

A Bu3P-mediated cyclization reaction of 3-cinnamoyl-4-hydroxy-2H-chromen-2-ones though electrophilic addition of acyl chlorides towards the synthesis of highly functionalized furo[3,2-c]coumarins bearing a phosphorus ylide moiety is described. These unprecedented cyclization reaction proceeds under mild reaction conditions within short reaction times (1 min to 1 h), and can be further applied in the synthesis of alkenyl-substituted furo[3,2-c]coumarins by the treatment with carbonyl electrophiles under basic conditions.

原文英語
頁(從 - 到)8502-8505
頁數4
期刊Angewandte Chemie - International Edition
54
發行號29
DOIs
出版狀態已發佈 - 2015 七月 13

ASJC Scopus subject areas

  • 催化
  • 化學 (全部)

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