Preparation of functional benzofurans, benzothiophenes, and indoles using ester, thioester, and amide via intramolecular wittig reactions

Siang En Syu, Yu Ting Lee, Yeong Jiunn Jang, Wenwei Lin*

*此作品的通信作者

研究成果: 雜誌貢獻期刊論文同行評審

49 引文 斯高帕斯(Scopus)

摘要

Preparation of new types of highly functional benzofurans, benzothiophenes, and indoles is realized via intramolecular Wittig reactions with the corresponding ester, thioester, and amide functionalities. The key intermediates, phosphorus ylides, presumably result from the addition of Bu 3P toward aldehydes followed by acylation and deprotonation. Synthesis of functional benzofurans directly starting from salicylic aldehyde derivatives with acid chlorides in a one-step procedure is also developed.

原文英語
頁(從 - 到)2970-2973
頁數4
期刊Organic Letters
13
發行號11
DOIs
出版狀態已發佈 - 2011 6月 3

ASJC Scopus subject areas

  • 生物化學
  • 物理與理論化學
  • 有機化學

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