Preparation of fluorescent silica nanotubes and their application in gene delivery

Chia Chun Chen, Yao Chung Liu, Chia Hsuan Wu, Chun Chia Yeh, Ming Tsan Su, Yi Chun Wu

研究成果: 雜誌貢獻文章

157 引文 斯高帕斯(Scopus)


The synthesis of fluorescent silica nanotubes with an inner diameter of hundreds of nanometer by sol-gel reaction using an anodic aluminum oxide (AAO) membrane as template and their application in gene delivery were discussed. It was found that a commercial AAO membrane with an average pore diameter of about 200 nm was employed as the template for silica nanotube preparation. The CdSe/ZnS core-shell nanocrystals with diameter of about 4 nm and 8 nm respectively were incorporated during nanotube preparation to generate green- and red-fluorescent silica nanotubes. Analysis suggest that the nanotube wall may act as a physical shield that protects the loaded DNA materials from potential environmental damage.

頁(從 - 到)404-407
期刊Advanced Materials
出版狀態已發佈 - 2005 二月 23


ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering