摘要
The carbometalation of (α-styryl)magnesium or -lithium organometallics with various allylic zinc bromides allows a general preparation of mixed benzylic 1, 1-dimetalloalkanes in good to excellent yields. Their low reactivity can be increased by a transmetalation with copper cyanide leading to copper, zinc dimetallic reagents which are readily bis-allylated with allyl bromide or bis-stannylated with trimethyltin chloride. Transmetalation with 1 equiv of trimethyltin chloride in the absence of copper salts affords tin, zinc 1, 1-dimetallo derivatives that can be cleanly oxidized by air to aromatic ketones under very mild conditions (-10 to 0 °C, 0.5-4 h). The monolithiation of the bis(trimethylstannyl) derivative 7 provides the a-lithiated benzylic tin compound 8 whose reactivity is also described.
原文 | 英語 |
---|---|
頁(從 - 到) | 2831-2835 |
頁數 | 5 |
期刊 | Organometallics |
卷 | 8 |
發行號 | 12 |
DOIs | |
出版狀態 | 已發佈 - 1989 12月 |
對外發佈 | 是 |
ASJC Scopus subject areas
- 物理與理論化學
- 有機化學
- 無機化學