Practical synthesis of 6-aryluridines via palladium(II) acetate catalyzed Suzuki-Miyaura cross-coupling reaction

Yu Chiao Shih; Tun Cheng Chien

doi:10.1016/j.tet.2011.03.051

Practical synthesis of 6-aryluridines via palladium(II) acetate catalyzed Suzuki-Miyaura cross-coupling reaction

Yu Chiao Shih, Tun Cheng Chien

化學系

研究成果: 雜誌貢獻 › 文章 › 同行評審

18 引文斯高帕斯（Scopus）

摘要

Sugar-protected 6-halouridine derivatives underwent Suzuki-Miyaura cross-coupling reactions with arylboronic acids in the presence of palladium(II) acetate as a catalyst, triphenylphosphine as a ligand, and sodium carbonate as a base. This methodology is applicable to both the C5- and C6-position of uridine and provides a direct access for versatile uridine derivatives.

原文	英語
頁（從 - 到）	3915-3923
頁數	9
期刊	Tetrahedron
卷	67
發行號	21
DOIs	https://doi.org/10.1016/j.tet.2011.03.051
出版狀態	已發佈 - 2011 五月 27

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tet.2011.03.051

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