Palladium-catalyzed tandem C-H functionalization/cyclization strategy for the synthesis of 5-hydroxybenzofuran derivatives

Sachin S. Ichake; Ashok Konala; Veerababurao Kavala; Chun Wei Kuo; Ching Fa Yao

doi:10.1021/acs.orglett.6b03310

Palladium-catalyzed tandem C-H functionalization/cyclization strategy for the synthesis of 5-hydroxybenzofuran derivatives

Sachin S. Ichake, Ashok Konala, Veerababurao Kavala, Chun Wei Kuo, Ching Fa Yao^*

^*此作品的通信作者

化學系

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

28 引文斯高帕斯（Scopus）

摘要

A palladium-catalyzed benzoquinone C-H functionalization/ cyclization strategy with terminal alkynes was employed for the synthesis of some biologically relevant 2, 3-disubstituted 5-hydroxybenzofuran derivatives. The benzoquinone acts as a reactant as well as an oxidant. During the process, an additional alkyne functionality can be introduced at the C3 position of the benzofuran. Base, ligand, and external oxidant are not required in this protocol.

原文	英語
頁（從 - 到）	54-57
頁數	4
期刊	Organic Letters
卷	19
發行號	1
DOIs	https://doi.org/10.1021/acs.orglett.6b03310
出版狀態	已發佈 - 2017 1月 6

ASJC Scopus subject areas

生物化學
物理與理論化學
有機化學

存取文件

10.1021/acs.orglett.6b03310

其它文件與鏈接

CCDC 1511959: Experimental Crystal Structure Determination
Ichake, S. S. (Creator), Konala, A. (Creator), Kavala, V. (Creator), Kuo, C. (Creator) & Yao, C. (Creator), Unknown Publisher, 2017
DOI: 10.5517/ccdc.csd.cc1mr9wk, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1mr9wk&sid=DataCite
資料集: Dataset
CCDC 1509527: Experimental Crystal Structure Determination
Ichake, S. S. (Creator), Konala, A. (Creator), Kavala, V. (Creator), Kuo, C. (Creator) & Yao, C. (Creator), Unknown Publisher, 2017
DOI: 10.5517/ccdc.csd.cc1mnsfh, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1mnsfh&sid=DataCite
資料集: Dataset
CCDC 1509374: Experimental Crystal Structure Determination
Ichake, S. S. (Creator), Konala, A. (Creator), Kavala, V. (Creator), Kuo, C. (Creator) & Yao, C. (Creator), Unknown Publisher, 2017
DOI: 10.5517/ccdc.csd.cc1mnmhd, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1mnmhd&sid=DataCite
資料集: Dataset

引用此

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abstract = "A palladium-catalyzed benzoquinone C-H functionalization/ cyclization strategy with terminal alkynes was employed for the synthesis of some biologically relevant 2, 3-disubstituted 5-hydroxybenzofuran derivatives. The benzoquinone acts as a reactant as well as an oxidant. During the process, an additional alkyne functionality can be introduced at the C3 position of the benzofuran. Base, ligand, and external oxidant are not required in this protocol.",

author = "Ichake, {Sachin S.} and Ashok Konala and Veerababurao Kavala and Kuo, {Chun Wei} and Yao, {Ching Fa}",

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AU - Kuo, Chun Wei

AU - Yao, Ching Fa

PY - 2017/1/6

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Palladium-catalyzed tandem C-H functionalization/cyclization strategy for the synthesis of 5-hydroxybenzofuran derivatives

摘要

ASJC Scopus subject areas

存取文件

其它文件與鏈接

指紋

資料集

CCDC 1511959: Experimental Crystal Structure Determination

CCDC 1509527: Experimental Crystal Structure Determination

CCDC 1509374: Experimental Crystal Structure Determination

引用此