Organocatalytic tandem three-component reaction of imine, alkyl vinyl ketone, and imide via aza-baylis-hillman reaction

Siang En Syu, Yu Ting Lee, Yeong Jiunn Jang, Wen-Wei Lin

研究成果: 雜誌貢獻文章同行評審

15 引文 斯高帕斯(Scopus)

摘要

A highly chemoselective PPh3-catalyzed three-component reaction of an imine, alkyl vinyl ketone, and phthalimide or succinimide is developed. Various highly functional adducts with high diastereoselectivities can be generated via aza-Morita-Baylis-Hillman reactions of aryl-substituted imines and alkyl vinyl ketones followed by Michael additions of imides and then epimerization.

原文英語
頁(從 - 到)2888-2891
頁數4
期刊Journal of Organic Chemistry
76
發行號8
DOIs
出版狀態已發佈 - 2011 四月 15

ASJC Scopus subject areas

  • Organic Chemistry

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