Optimization of a simple method for the chiral separation of methamphetamine and related compounds in clandestine tablets and urine samples by β-cyclodextrine modified capillary electrophoresis: A complementary method to GC-MS

An Shu Liau, Ju Tsung Liu, Li Chan Lin, Yu Chih Chiu, You Ren Shu, Chung Chen Tsai, Cheng Huang Lin

研究成果: 雜誌貢獻文章

46 引文 斯高帕斯(Scopus)

摘要

The chiral separation of (±)-methamphetamine, (±)-methcathinone, (±)-ephedrine and (±)-pseudoephedrine by means of β-cyclodextrine modified capillary electrophoresis is described. The distribution of enantiomers in clandestine tablets and urine samples were identified. Several electrophoretic parameters such as the concentration of β-cyclodextrin, temperature, the applied voltage and the amount of organic solvent required for successful separation were optimized. The method, as described herein, represents a good complementary method to GC-MS for use in forensic and clinical analysis.

原文英語
頁(從 - 到)17-24
頁數8
期刊Forensic Science International
134
發行號1
DOIs
出版狀態已發佈 - 2003 六月 24

    指紋

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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