One-pot synthesis of the hydroximoyl chlorides and [3.3.0] bicyclic compounds from the reactions of β-nitrostyrenes with stabilized nucleophiles

Kuo Hsi Kao; Cherng Shi Yang; Ju Tsung Liu; Wen Wei Lin; Hui Yu Fang; Ching Fa Yao; Kwunmin Chen

doi:10.1016/S0040-4020(98)00883-7

One-pot synthesis of the hydroximoyl chlorides and [3.3.0] bicyclic compounds from the reactions of β-nitrostyrenes with stabilized nucleophiles

Kuo Hsi Kao
, Cherng Shi Yang
, Ju Tsung Liu
, Wen Wei Lin
, Hui Yu Fang
, Ching Fa Yao^*
, Kwunmin Chen

^*此作品的通信作者

化學系

研究成果: 雜誌貢獻 › 期刊論文 › 同行評審

20 引文斯高帕斯（Scopus）

摘要

β-Nitrostyrenes 1 react with various stabilized nucleophiles to generate hydroximoyl chlorides and nitroalkanes after workup with ice cold concentrated hydrochloric acid. One-pot synthesis of bicyclic products from the Michael addition of different nucleophiles with β-nitrostyrenes 1 is reported.

原文	英語
頁（從 - 到）	13997-14014
頁數	18
期刊	Tetrahedron
卷	54
發行號	46
DOIs	https://doi.org/10.1016/S0040-4020(98)00883-7
出版狀態	已發佈 - 1998 11月 12

ASJC Scopus subject areas

生物化學
藥物發現
有機化學

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10.1016/S0040-4020(98)00883-7

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@article{1b63ec015c1842339eb92f153f58b8d5,

title = "One-pot synthesis of the hydroximoyl chlorides and [3.3.0] bicyclic compounds from the reactions of β-nitrostyrenes with stabilized nucleophiles",

abstract = "β-Nitrostyrenes 1 react with various stabilized nucleophiles to generate hydroximoyl chlorides and nitroalkanes after workup with ice cold concentrated hydrochloric acid. One-pot synthesis of bicyclic products from the Michael addition of different nucleophiles with β-nitrostyrenes 1 is reported.",

author = "Kao, \{Kuo Hsi\} and Yang, \{Cherng Shi\} and Liu, \{Ju Tsung\} and Lin, \{Wen Wei\} and Fang, \{Hui Yu\} and Yao, \{Ching Fa\} and Kwunmin Chen",

note = "Funding Information: Financial support by the National Science Council of the Republic of China (Grants NSC 87-2113-M-003-010 and NSC 87-2113-M-324-001) and X-ray data are collected and processed by Professor C.-H. Ueng of National Taiwan Normal University are gratefully acknowledged.",

year = "1998",

month = nov,

day = "12",

doi = "10.1016/S0040-4020(98)00883-7",

language = "English",

volume = "54",

pages = "13997--14014",

journal = "Tetrahedron",

issn = "0040-4020",

publisher = "Elsevier Limited",

number = "46",

}

TY - JOUR

T1 - One-pot synthesis of the hydroximoyl chlorides and [3.3.0] bicyclic compounds from the reactions of β-nitrostyrenes with stabilized nucleophiles

AU - Kao, Kuo Hsi

AU - Yang, Cherng Shi

AU - Liu, Ju Tsung

AU - Lin, Wen Wei

AU - Fang, Hui Yu

AU - Yao, Ching Fa

AU - Chen, Kwunmin

N1 - Funding Information: Financial support by the National Science Council of the Republic of China (Grants NSC 87-2113-M-003-010 and NSC 87-2113-M-324-001) and X-ray data are collected and processed by Professor C.-H. Ueng of National Taiwan Normal University are gratefully acknowledged.

PY - 1998/11/12

Y1 - 1998/11/12

N2 - β-Nitrostyrenes 1 react with various stabilized nucleophiles to generate hydroximoyl chlorides and nitroalkanes after workup with ice cold concentrated hydrochloric acid. One-pot synthesis of bicyclic products from the Michael addition of different nucleophiles with β-nitrostyrenes 1 is reported.

AB - β-Nitrostyrenes 1 react with various stabilized nucleophiles to generate hydroximoyl chlorides and nitroalkanes after workup with ice cold concentrated hydrochloric acid. One-pot synthesis of bicyclic products from the Michael addition of different nucleophiles with β-nitrostyrenes 1 is reported.

UR - https://www.scopus.com/pages/publications/0032512081

UR - https://www.scopus.com/pages/publications/0032512081#tab=citedBy

U2 - 10.1016/S0040-4020(98)00883-7

DO - 10.1016/S0040-4020(98)00883-7

M3 - Article

AN - SCOPUS:0032512081

SN - 0040-4020

VL - 54

SP - 13997

EP - 14014

JO - Tetrahedron

JF - Tetrahedron

IS - 46

ER -

One-pot synthesis of the hydroximoyl chlorides and [3.3.0] bicyclic compounds from the reactions of β-nitrostyrenes with stabilized nucleophiles

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ASJC Scopus subject areas

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