摘要
The nucleophilic allylation of various chiral auxiliaries derived glyoxylic oxime ethers was studied. The use of allyltributylstannane in the presence of a Lewis acid and triallylaluminum provided the corresponding homoallylic amines in high chemical yields (up to 89%) and excellent stereoselectivities (up to >99%). The stereochemical bias of the allylation is proposed.
原文 | 英語 |
---|---|
頁(從 - 到) | 7816-7822 |
頁數 | 7 |
期刊 | Tetrahedron |
卷 | 63 |
發行號 | 33 |
DOIs | |
出版狀態 | 已發佈 - 2007 8月 13 |
ASJC Scopus subject areas
- 生物化學
- 藥物發現
- 有機化學
指紋
深入研究「On the scope of diastereoselective allylation of various chiral glyoxylic oxime ethers with allyltributylstannane in the presence of a Lewis acid and triallylaluminum」主題。共同形成了獨特的指紋。資料集
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CCDC 642117: Experimental Crystal Structure Determination
Kulkarni, N. A. (Creator), Yao, C.-F. (Creator) & Chen, K. (Creator), Unknown Publisher, 2007
DOI: 10.5517/ccpk5gv, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccpk5gv&sid=DataCite
資料集: Dataset
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CCDC 642120: Experimental Crystal Structure Determination
Kulkarni, N. A. (Creator), Yao, C.-F. (Creator) & Chen, K. (Creator), Unknown Publisher, 2007
DOI: 10.5517/ccpk5ky, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccpk5ky&sid=DataCite
資料集: Dataset
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CCDC 642119: Experimental Crystal Structure Determination
Kulkarni, N. A. (Creator), Yao, C.-F. (Creator) & Chen, K. (Creator), Unknown Publisher, 2007
DOI: 10.5517/ccpk5jx, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccpk5jx&sid=DataCite
資料集: Dataset