TY - JOUR
T1 - On-line identification of 3,4-methylenedioxymethamphetamine in human urine by non-aqueous capillary electrophoresis-fluorescence spectroscopy at 77 K
AU - Chung, Yu Lin
AU - Liu, Ju Tsung
AU - Lin, Cheng Huang
N1 - Funding Information:
This work was supported by a grant from the National Science Council of Taiwan under contract No. NSC-89-2113-M-003-016. Permission was obtained from Pharmaceutical Affairs, Department of Health, Taiwan (license No.: ARR089000035). The authors would like to thank the Forensic Science Center (Taiwan Command of the Army Force of Military Police) for generously donating the urine samples and amphetamine standards.
PY - 2001/8/15
Y1 - 2001/8/15
N2 - The analytical profiles for 3,4-methylenedioxymethamphetamine (3,4-MDMA) and related amphetamines in urine samples are described for non-aqueous capillary electrophoresis-fluorescence spectroscopy. 3,4-MDMA was detected and identified on-line, using a cryogenic molecular fluorescence technique at 77 K. Under optimized conditions, baseline separation of the selected compounds was achieved in less than 12 min. Precision was evaluated by measuring the repeatability and intermediate precision of the migration times and corrected peak areas. The non-aqueous CE separation conditions and the spectral characteristics of 3,4-MDMA with respect to solvent and temperature effects are also discussed.
AB - The analytical profiles for 3,4-methylenedioxymethamphetamine (3,4-MDMA) and related amphetamines in urine samples are described for non-aqueous capillary electrophoresis-fluorescence spectroscopy. 3,4-MDMA was detected and identified on-line, using a cryogenic molecular fluorescence technique at 77 K. Under optimized conditions, baseline separation of the selected compounds was achieved in less than 12 min. Precision was evaluated by measuring the repeatability and intermediate precision of the migration times and corrected peak areas. The non-aqueous CE separation conditions and the spectral characteristics of 3,4-MDMA with respect to solvent and temperature effects are also discussed.
KW - 3,4-Methylenedioxymethamphetamine
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U2 - 10.1016/S0378-4347(01)00225-0
DO - 10.1016/S0378-4347(01)00225-0
M3 - Article
C2 - 11499475
AN - SCOPUS:0035882758
SN - 1387-2273
VL - 759
SP - 219
EP - 226
JO - Journal of Chromatography B: Biomedical Sciences and Applications
JF - Journal of Chromatography B: Biomedical Sciences and Applications
IS - 2
ER -