@article{6f775f52e2f84e3abfc7cb5e5f5fce4a,
title = "Oleic acid-enhanced transdermal delivery pathways of fluorescent nanoparticles",
abstract = "Transdermal delivery of nanocarriers provides an alternative pathway to transport therapeutic agents, alleviating pain, improving compliance of patients, and increasing overall effectiveness of delivery. In this work, enhancement of transdermal delivery of fluorescent nanoparticles and sulforhodamine B with assistance of oleic acid was visualized utilizing multiphoton microscopy (MPM) and analyzed quantitatively using multi-photon excitation-induced fluorescent signals. Results of MPM imaging and MPM intensity-based spatial depth-dependent analysis showed that oleic acid is effective in facilitating transdermal delivery of nanoparticles.",
author = "Wen Lo and Ara Ghazaryan and Tso, {Chien Hsin} and Hu, {Po Sheng} and Chen, {Wei Liang} and Kuo, {Tsung Rong} and Lin, {Sung Jan} and Chen, {Shean Jen} and Chen, {Chia Chun} and Dong, {Chen Yuan}",
note = "Funding Information: Funding support for this work was provided by Taiwan{\textquoteright}s National Science Council (NSC 99-2221-E-002-096-MY3, 99-2221-E-002-096-MY3), National Health Research Institute (NHRI-EX100-10041EI), Center for Quantum Science and Engineering of National Taiwan University (CQSE-99R80870), and National Taiwan University (NTU-99R70409).",
year = "2012",
month = may,
day = "21",
doi = "10.1063/1.3701135",
language = "English",
volume = "100",
journal = "Applied Physics Letters",
issn = "0003-6951",
publisher = "American Institute of Physics Publising LLC",
number = "21",
}