Nucleosides XIII. Facile synthesis of 4-amino-1-(2-deoxy-β-D- ribofuranosyl)quinazolin-2-one as a 2′-deoxycytidine analog for oligonucleotide synthesis

Tun Cheng Chien, Chien Shu Chen, Ji Wang Chern

研究成果: 雜誌貢獻文章

6 引文 (Scopus)

摘要

4-Amino-1-(2-deoxy-β-D-ribofuranosyl)quinazo1in-2-one (4) was prepared by Barton deoxygenation from 4-amino-1-(β-D-ribofuranosyl)quinazolin-2-one (3) as a 2′-deoxycytidine analog.

原文英語
頁(從 - 到)1237-1244
頁數8
期刊Journal of the Chinese Chemical Society
52
發行號6
DOIs
出版狀態已發佈 - 2005 一月 1

指紋

Deoxycytidine
Nucleosides
Oligonucleotides

ASJC Scopus subject areas

  • Chemistry(all)

引用此文

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abstract = "4-Amino-1-(2-deoxy-β-D-ribofuranosyl)quinazo1in-2-one (4) was prepared by Barton deoxygenation from 4-amino-1-(β-D-ribofuranosyl)quinazolin-2-one (3) as a 2′-deoxycytidine analog.",
keywords = "2′-Deoxycytidine, Barton deoxygenation, Cytidine, Markiewicz silylation, Quinazolinone",
author = "Chien, {Tun Cheng} and Chen, {Chien Shu} and Chern, {Ji Wang}",
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T1 - Nucleosides XIII. Facile synthesis of 4-amino-1-(2-deoxy-β-D- ribofuranosyl)quinazolin-2-one as a 2′-deoxycytidine analog for oligonucleotide synthesis

AU - Chien, Tun Cheng

AU - Chen, Chien Shu

AU - Chern, Ji Wang

PY - 2005/1/1

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N2 - 4-Amino-1-(2-deoxy-β-D-ribofuranosyl)quinazo1in-2-one (4) was prepared by Barton deoxygenation from 4-amino-1-(β-D-ribofuranosyl)quinazolin-2-one (3) as a 2′-deoxycytidine analog.

AB - 4-Amino-1-(2-deoxy-β-D-ribofuranosyl)quinazo1in-2-one (4) was prepared by Barton deoxygenation from 4-amino-1-(β-D-ribofuranosyl)quinazolin-2-one (3) as a 2′-deoxycytidine analog.

KW - 2′-Deoxycytidine

KW - Barton deoxygenation

KW - Cytidine

KW - Markiewicz silylation

KW - Quinazolinone

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JF - Journal of the Chinese Chemical Society

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