Monitoring chemically enhanced transdermal delivery pathways of luminescent quantum dots by multiphoton microscopy

Wen Lo, Chien Hsin Tso, Pei Yue Huang, Chih Lung Hsu, Chun Chia Yeh, Sung Jan Lin, Shiou Hwa Jee, Chia Chun Chen, Chen Yuan Dong*

*此作品的通信作者

研究成果: 書貢獻/報告類型會議論文篇章

1 引文 斯高帕斯(Scopus)

摘要

Luminescent quantum dots (QDs) are attractive fluorescent probes in bioimaging application. In this work, we investigate the feasibility of administering QDs (7 nm in size) through transdermal delivery pathway using multiphoton fluorescence imaging. Our results show that QDs of this size range can be effectively delivered through intercellular pathways using the chemical enhancer oleic acid. This work has implications for understanding the transport of important biological macromolecules. Our results suggest that QDs can be non-invasively delivered for biological imaging and for probing the transport of nanometer-scale material in tissue. These results also imply that the size of nanoparticles may dominate the nature of transdermal transport mechanism.

原文英語
主出版物標題Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004
頁面74-75
頁數2
出版狀態已發佈 - 2004
事件Second Asian and Pacific Rim Symposium on Biophotonics, APBP 2004 - Taipei, 臺灣
持續時間: 2004 十二月 152004 十二月 17

出版系列

名字Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004

其他

其他Second Asian and Pacific Rim Symposium on Biophotonics, APBP 2004
國家/地區臺灣
城市Taipei
期間2004/12/152004/12/17

ASJC Scopus subject areas

  • 工程 (全部)

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