Magnetic susceptibility reduction method for magnetically labeled immunoassay

Chin Yih Hong, C. C. Wu, Y. C. Chiu, S. Y. Yang, H. E. Horng, H. C. Yang

    研究成果: 雜誌貢獻文章同行評審

    135 引文 斯高帕斯(Scopus)

    摘要

    In addition to synthesizing biofunctionalized magnetic nanopaticles for the purpose of magnetically labeling biomolecules, a system to measure the ac magnetic susceptibility of the labeled sample was developed. When a targeted biomolecule was mixed with magnetic fluid possessing biofunctionalized magnetic nanoparticles, portions of magnetic nanoparticles agglomerated to form clusters due to the association with the targeted biomolecule. Due to the formation of magnetic clusters, the measured ac magnetic susceptibility reduced. The relationship between the mixed-frequency ac magnetic susceptibility reduction and the amount of the detected biomolecule was established.

    原文英語
    文章編號212512
    期刊Applied Physics Letters
    88
    發行號21
    DOIs
    出版狀態已發佈 - 2006 五月 21

    ASJC Scopus subject areas

    • Physics and Astronomy (miscellaneous)

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